Simon Vozick-Levinson of Entertainment Weekly gave the song a positive review, as while he said "This is, more or less, the Eminem I've been waiting for. The censored version removes references of killing or murder, but the music video keeps the words in. The song has a much darker concept than most of Relapse 's songs, which are generally more humorous, which sets it aside greatly from much of the album. The beginning of the song uses a sample of "Ghost of Love" by Timeless Legend.
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He later referenced the movie again in the track "Buffalo Bill" from Relapse: Refill. This is the third time Eminem uses a reference to The Silence of the Lambs, to which Eminem also referred in the D12 song "American Psycho" from Devil's Night and the music video for " You Don't Know" from The Re-Up. She puts the lotion in the bucket, she puts the lotion on her skin, or else she will get the hose again.'). The song contains a line from The Silence of the Lambs ('She puts the lotion in the bucket, she puts the lotion on her skin. It features Eminem presumably rapping from the perspective of his alter ego Slim Shady, using both internal and multi-syllabic rhyme schemes in his three verses. It's meant to be an ode to his fascination with horror movie characters such as Freddy Krueger and Hannibal Lecter. The song, according to Eminem, is said to be closer to the overall sound of the album, as opposed to the poppy, fun-poking " We Made You".
Eminem raps from the perspective of a serial killer questioning his own sanity and recalling a string of murders.